程輝，中國醫(yī)學(xué)科學(xué)院血液病醫(yī)院（血研所）研究員，協(xié)和準長聘助理教授，博導(dǎo)。2007年獲浙江大學(xué)學(xué)士學(xué)位。2013年獲北京協(xié)和醫(yī)學(xué)院博士學(xué)位。研究方向為造血干細胞及其微環(huán)境。以第一/通訊作者（含共同）在Nat Cell Biol、J Clin Invest、J Exp Med、Blood等雜志上發(fā)表論文和綜述20余篇。國家重點研發(fā)計劃首席科學(xué)家。獲國家優(yōu)青、天津市杰青等人才項目。獲國家自然科學(xué)獎二等獎。獲國內(nèi)外專利5項。中國生理學(xué)會青年委員和天津市血液與再生醫(yī)學(xué)學(xué)會理事。

作為最早被應(yīng)用于臨床的成體干細胞，造血干細胞（HSC）功能和分化模式一直以來是研究的熱點。我們實驗室的研究目標是明確HSC在穩(wěn)態(tài)和疾病狀態(tài)下的內(nèi)外調(diào)控機制，揭示微環(huán)境在其中的變化規(guī)律繼而對HSC的影響機理，探討HSC選擇性保護的分子機制，以期為白血病的治療提供新的思路和策略。

爆草黑丝美女|韩国19禁无遮挡啪啪无码网站|91精品国产自产精品男人的天堂|sm鞭打高潮喷水抽搐调教玩弄

1. Yang S.#, Sun G.#, Wu P.#, Chen C.#, Kuang Y., Liu L., Zheng Z., He Y., Gu Q., Lu T., Zhu C., Wang F., Gou F., Yang Z., Zhao X., Yuan S., Yang L., Lu S., Li Y., Lv X., Dong F., Ma Y., Yu J., Ng L., Shi L., Liu J.*, Shi L.*, Cheng T.*, Cheng H.*. WDR82-binding long non-coding RNA lncEry controls mouse erythroid differentiation and maturation. J Exp Med. 2022; 219(4). (IF= 17.579)

2. Wang T.#, Xia C.#, Weng Q., Wang K., Dong Y., Hao S., Dong F., Liu X., Liu L., Geng Y., Guan Y., Du J., Cheng T., Cheng H.*, Wang J*. Loss of Nupr1 promotes engraftment by tuning the quiescence threshold of hematopoietic stem cell repository via regulating p53-checkpoint pathway. Haematologica. 2022; 107(1). (IF=11.047)

3. Wang FJ.#, He J.#, Liu S.#, Gao A., Yang L., Sun G., Ding W., Li C., Wang F., Wang X., Zhu P., Hao S., Ma Y.*, Cheng H.*, Yu J.*, Cheng T*. Comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation. Blood. 2021;138(20). (IF=25.476)

4. Yuan S., Sun G., Zhang Y., Dong F., Cheng H.*, Cheng T*. Understanding the ‘SMART’ features of hematopoietic stem cells and beyond. Sci China Life Sci. 2021;64(12). (IF=10.372)

5. Huang D.#, Sun G.#, Hao X.#, He X.#, Zheng Z., Chen C., Yu Z., Xie L., Ma S., Liu L., Zhou B., Cheng H.*, Zheng J.*, and Cheng T*. ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression. J Clin Invest. 2021;131(1). (IF=19.456)

6. Zhang C.#, Xu Z.#, Yang S.#, Sun G.#, Jia L., Zheng Z., Gu Q., Tao W.*, Cheng T.*, Li C.* and Cheng H.*. tagHi-C reveals 3D chromatin architecture dynamics during hematopoiesis. Cell Rep. 2020;32(13). (IF=9.423)

7.   Dong F., Cheng H.*, Ema H.*, Cheng T*. Probing the fate of transplanted hematopoietic stem cells: is the combinational approach "FIT" for purpose? Sci China Life Sci. 2020;63(11):1755-8. (IF=6.037)

8.   Dong F.#, Hao S.#, Zhang S.#, Zhu C.#, Cheng H.#, et al. Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis. Nat Cell Biol. 2020;22(6):630-9. (IF=28.824)

9.   Xia C.#, Wang T.#, Cheng H.#, et al. Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment. Leukemia. 2020;34(9):2375-83. (IF=11.528)

10. Ma S.#, Sun G.#, Yang S., Ju Z.*, Cheng T.*, Cheng H.*. Effects of telomere length on leukemogenesis. Sci China Life Sci. 2020;63(2):308-11. (IF=6.037)